For a thorough review presentation see the video below:

Franco RSO. Pappa A. Panayiotidis MI. The central role of glutathione in the pathophysiology of human disease. Arch Physiol Biochem. 2007;113:234–258.

Wu G. Fang YZ. Yang S, et al. Glutathione metabolism and its implications for health. J Nutr. 2004;134:489–492.

Vitamin C

Douglas R, Hemila H, Chalker E, et al. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev 2007;(3):CD00980


Zollinger PE, Tuinbreijer WE, Breederveld RS, et al. Can vitamin C prevent complex regional pain syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response study J Bone Joint Surg Am 2007;89(7):1424-1431


Zojaji H, Talaie R, Mirsattari D, et al. The efficacy of Helicobacter pylori eradication regimen with and without vitamin C supplementation. Dig Liver Dis 2009; 41(9): 644-647


Proctor M.L., Murphy P.A.: Herbal dietary therapies for primary and secondary dysmenorrhoea. Cochrane Database Syst Rev. 2 2002 CD002124


Kazaks A., Uriu-Adams J., Albertson T., et al.: Effect of magnesium supplementation on measures of airway resistance and subjective assessment of asthma control and quality of life in men and women with mild to moderate asthma: a randomized placebo controlled trial. J Asthma.. 47:83-92 2010 PMID20100026


Hatzistavri LS, P.A. D, Georgianos P.I., et al. Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension. Am J Hypertens 2009;22:1070-1075


Facchinetti F, Borella P, Sances G, et al. Oral magnesium successfully alleviates premenstrual symptoms of fluid retention. J Womens Health 1998; 7: 1157-1165.


De Souza MC, Walker AF, Robinson PA, Bolland K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety related premenstrual symptoms: a randomized , double-blind crossover study. J Women’s Health Gend Based Med 2000; 9:131-139.


Peikert A, Wilimzig C, Kohne-Volland R.  Prophylaxis of migraine with oral magnesium:results from a progressive multi-center placebo-controlled and double blind randomized study. Cephalgia 1996; 16:257-263


Practice Bulletin No. 153: Nausea and vomiting of pregnancy. September 2015. American College of Obstet Gynecol 2015;126:e12-24. Full text of ACOG Practice Bulletins is available to ACOG members at


Sanfilippo J., Erb T.: Evaluation and management of dysmenorrhea in adolescents. Clin Obstet Gynecol. 51:257-267 2008 PMID18463457


Boehnke C., Reuter U., Flach U., et al.: High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. Eur J Neurol. 11:475-477 2004 PMID15257686


Williams A.L., Cotter A., Sabina A., et al.: The role for vitamin B-6 as treatment for depression: a systematic review. Fam Pract. 22:532-537 2005 PMID15964874


Wyatt K.M., Dimmock P.W., Jones P.W., et al.: Efficacy of vitamin B6 in the treatment of premenstrual syndrome: systematic review. BMJ.. 318:1375-1381 1999 10334745


Morris, MS. The Role of B Vitamins in Preventing and Treating Cognitive Impairment and Decline. Adv Nutr 2012;  Nov 3 (6):801-812.


Lindenbaum J., Healton E.B., Savage D.G., et al.: Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytoses. N Engl J Med. 318:1720-1728 1988


Beck W.S.: Cobalamin and the nervous system [editorial]. N Engl J Med. 318:1752-1754 1988 PMID 3374546

Vitamin D

Ginde A., Mansbach J., Camargo C.: Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med.. 169:384-390 2009 PMID19237723


Straube S., Derry S., Moore R.A., et al.: Vitamin D for the treatment of chronic painful conditions in adults. Cochrane Database Syst Rev.. (1)2010 CD007771

Vitamin E

28Natural Medicines Comprehensive Database: Vitamin E.